Tissue	Disease	Species	symbol	ID	Platform	Type	Expression	Target	Pathway	Method	Drug	Function	PMID	Title	Year	
heart	acute_myocardial_infarction	rattus_norvegicus	Tug1	100125371	Gene	lncrna	up-regulation	NA	TGF-BETA SIGNALING PATHWAY	cell counting kit-8;transwell assays;western blot	no	TUG1 expression was increased in AMI tissue and cardiac fibroblasts treated with TGF-beta1. TUG1 knockdown suppressed the biological process of cardiac fibroblasts treated with TGF-beta1 by sponging miR-590.	34341870	TUG1 knockdown suppresses cardiac fibrosis after myocardial infarction	https://pubmed.ncbi.nlm.nih.gov/34341870/	2021
heart	myocardial_infarction	rattus_norvegicus	Tug1	100125371	Gene	lncrna	up-regulation	NA	NA	luciferase activity;RIP experiments	no	TUG1 knockdown inhibited the Ang-II induced cardiac myofibroblast activation and TUG1 overexpression increased proliferation and collagen generation of cardiac myofibroblasts.	34553456	LncRNA TUG1 acts as a competing endogenous RNA to mediate CTGF expression by sponging miR-133b in myocardial fibrosis after myocardial infarction	https://pubmed.ncbi.nlm.nih.gov/34553456/	2021